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Details
Posted: 06-Sep-25
Location: Springfield, IL
Internal Number: 5070361
aims of two laboratories' NIH-funded grants under the direction of two laboratory Principle
Investigator (PI), Drs. Don Caspary and Ben Richardson (brichard@siu.edu) in the Department
of Pharmacology at Southern Illinois University School of Medicine in Springfield, IL. Broadly, this
laboratory addresses issues in understanding neural circuits and their role in disease using a
multi-level state-of-the-art approach. The primary activities of the Fellow will be to perform whole
cell electrophysiology, in vivo electrophysiology, rodent behavioral assays, viral injections in
rodents, microscopy, and training of students and laboratory staff.
The main role of the Fellow is to design and execute studies aimed at understanding the
neurological basis of altered synaptic function in the auditory midbrain with aging and in
neurodevelopmental disorder animal models, including Autism Spectrum Disorder. Parallel to
physiological studies, a transgenic approach will be used to determine how cellular level changes
may lead to disrupted motor and non-motor behaviors. Finally, the fellow may contribute to in vivo
recording studies in wildtype and mutant mice to determine how cellular and synaptic level
changes affect activity of the cerebellar circuit in vivo.
The position is one year in duration and will be renewed annually based on Fellow performance
and funding availability.
1. Help obtain information relevant to making purchase decisions.
2. Direct the management and genotyping of the animal colony in conjunction with
research staff.
3. Help order approved laboratory supplies and reagents.
4. Assist with scheduling experiments, laboratory equipment usage and availability.
II. Teaching 15 %
1. Assist in training students and laboratory staff.
III. Research 75 %
1. Conduct investigator-initiated and independent research projects under the
general supervision of the PI or in conjunction with graduate students.
2. Perform and design electrophysiology recordings from model system central
nervous system.
3. Perform and design survival viral injection surgery in rodents.
4. Perform or direct histological preparation (including microscopy) and
neurochemical procedures consistent with the project.
5. Prepare reagents used for experiments with accuracy and consistency.
6. Perform data reduction and analysis and preparation for oral and written
dissemination.
7. Maintain detailed records of laboratory work performed.
IV. Service 0%
PhD in an appropriate field (e.g. pharmacology, biology, neuroscience, etc.).
Experience in electrophysiology.
Sensitive to the needs of underrepresented minority populations.
DESIRABLE QUALIFICATIONS
Experience in data analysis and preparation for publication.
Excellent written and oral communication skills.
Self-motivated, well-organized, detail-oriented, displays initiative.
Ability to work well in a team and independently.
Previous experience working with mice or rats.
About Southern Illinois University - School of Medicine
SIU School of Medicine was established in 1970 with a mission to educate physicians for central and southern Illinois. We are a medical school with four areas of excellence: medical education, patient care, research and community service. SIU School of Medicine provides education to undergraduate medical students, medical and surgical residents, fellows, and physician assistant students. Our clinical practice, SIU Medicine, includes a team of more than 250 health care professionals including university physicians and faculty members who are collectively dedicated to providing excellent medical care, advancement of care through research, and training the next generation of physicians. As the premier provider of health care services, SIU Medicine offers both primary care and specialized treatment services including preventative and diagnostic. SIU works in partnership with hospitals and clinics throughout central and southern Illinois to meet the health care needs of our communities.
More Jobs from This Employer
https://careers.iecaonline.com/jobs/21644858/post-doctoral-fellow-sms-3731
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