UCSD Layoff from Career Appointment: Apply by 03/03/8/23 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 03/20/23. Eligible Special Selection clients should contact their Disability Counselor for assistance.
Job posting will remain open until a suitable candidate has been identified.
DESCRIPTION
Under supervision, incumbent will manage the satellite mouse facility. Work with Animal Care Program to coordinate mouse deliveries, housing and daily care. Manage mouse breeding colonies, including genotyping and mating. Provide technical training and assistance to lab members. Attend lab meetings and contribute to the discussions on research. Manage AALAS compliance, personnel training, lab safety, lab equipment and supplies. Maintain laboratory infrastructure, manage records, take inventory and order supplies for the lab. Manage animal resources, providing guidance to other lab members for animal care.
Under supervision, the incumbent will assist with research projects working with laboratory animals. Apply conventional methods, combining neuroanatomical, histological and behavioral approaches, perform experiments that aim to identify neural activity underlying behavior and learning. Implement laboratory and surgical protocols and provide training to staff lab assistants, postdocs, graduate and undergraduate students in same. Perform other duties as assigned.
QUALIFICATIONS
Graduation from high school or a GED and three (3) years of laboratory experience or two (2) years of college including courses in biochemistry, molecular biology or genetics and two (2) years of laboratory experience; or an equivalent combination of education and experience; and knowledge and abilities essential to the successful performance of the duties assigned to the position.
Experience working with mice in laboratory setting. Must be proficient in handling them. Experience in behavioral studies with rodents preferred.
Experience in managing mouse colonies, including genotyping, crossing and creating and maintaining accurate breeding records.
Knowledge of animal protocols and experience with animal care procedures, husbandry, anesthesia/analgesia requirements, postoperative care, euthanasia, experimental use records and carcass disposal of UCSD or another accredited institute.
Practical knowledge of cellular, molecular, and genetic biology, with demonstrated ability to perform independent scientific inquiry in neurobiology.
Experience in small rodent surgery including anesthesiology procedures and chemical injections. Excellent experience and ability to perform brain surgeries, including precise and stereotaxic injections of dyes and viruses, and adaptive use of different brain atlases for precise injections of tracer compounds.
Good hand/eye coordination and surgical skills and knowledge for fine dissection. Ability to learn new surgical techniques with minimal instructions. Ability to improve surgical protocols independently when possible.
Demonstrated skills in histology, including perfusion, brain sectioning, immunostaining, routine neurohistology staining (e.g. Nissl and myelin), counterstaining including Giemsa and toluidin blue, labeling enhancement (gold, silver, nickel) and imaging (both epi and confocal).
Experience in stoichiometry and chemistry for preparation of histological reagents, immunocytochemistry, and laboratory stock solutions. Knowledge of necessary care and precautions for use and storage of antisera, reagents, and for handling of hazardous and carcinogenic chemicals.
Proven ability to develop, follow and trouble-shoot established lab protocols and lab procedures with direction from PI.
Ability to coordinate research projects and provide work direction as needed to lab personnel.
Ability to learn the scientific research of lab. Willingness and ability to learn new skills, research methods, and scientific principles.
Extensive knowledge/understanding and experience with Safety Data Sheets, hazard communication and Injury and Illness Prevention Program. Familiarity with a Chemical Hygiene Plan addressing safety precautions including appropriate clothing and shoes, safe handling of chemicals, use of protective items. Willingness and ability to keep safety training current and consistent with research involvement.
Well-versed with federal guidelines for Good Laboratory Practices for humane use of animals. AAALAC or AALAS certifications desirable. Knowledge of research animal care protocols and procedures as defined by AAALAC and AALA
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.
