Fremont, California
Sacramento, California
Saint Bonifacius, Minnesota
Stillwater, Oklahoma
Aurora, Colorado
Pennington, NJ / Hybrid & Flexible Work Options Available
Grand Rapids, Michigan
Chapel Hill, North Carolina
La Jolla, California
New York, NY, 10176, USA
South Abington Township, Pennsylvania
Posted: 02-Mar-23
Location: La Jolla, California
Salary: Open
Internal Number: 121777
This position will remain open until a successful candidate has been identified.
UCSD Layoff from Career Appointment: Apply by 03/03/2023 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 03/14/2023. Eligible Special Selection clients should contact their Disability Counselor for assistance.
DESCRIPTION
The Moores Cancer Center is one of just 53 NCI-designated Comprehensive Cancer Centers in the United States and the only one in San Diego County. As a consortium cancer center, it is a collaborative partnership between the UCSD: encompassing 14 departments (12 clinical, 2 basic sciences), 3 professional schools (School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, School of Public Health), UCSD Health oncology hospitals and clinics; the basic and public health research and outreach of San Diego State University, and the basic and translational research of the La Jolla Institute of Immunology.
These various programs and units are all dedicated to fulfilling the Moores Cancer Center's mission of reducing cancer's burden. As such, it ranks among the top centers in the nation conducting the continuum of cancer research, providing advanced patient care, and serving the community through outreach and education programs. As a top-ranking, future-oriented organization, we offer challenging career opportunities in a fast-paced and innovative environment. Moores Cancer Center follows a progressive philosophy of career-path development for its employees including opportunities for cross-training, professional development, and progressive responsibility.
MCC's mission is to transform cancer care in our catchment area and beyond by driving exceptional scientific discoveries, and innovations in prevention, detection, care, and training. MCC will make a global impact on improving health by reducing cancer burden through accelerated discovery and translation, compassionate and interdisciplinary care, education and community engagement, with the foundation of our core values - Excellence, Innovation and Risk-Taking, Collaboration, Diversity and Service.
Within a leading blood cancer research laboratory, the incumbent will perform duties in a Hematology/Oncology research laboratory specializing in Chronic Lymphocytic Leukemia (CLL). This laboratory receives samples from patients with leukemia, runs clinical trials, conducts experiments on the patient samples to evaluate and understand the biology of this leukemia.
Under supervision, the incumbent will participate in molecular biology experiments, organize the data, and prepare summaries for the supervisor. Incumbent will perform specific molecular biology techniques including DNA isolation for sequencing specific leukemia genes, RNA isolation, cDNA synthesis, PCR, RT-PCR, agarose and SDS PAGE electrophoresis, western blotting. Independently perform sterile tissue culture techniques, including processing patient samples and storing patient samples per protocols and established lab procedures. Review new protocols to characterize the patient samples related to targeted genome sequencing and independently perform and analyze flow cytometry data using FlowJo software.
Responsible for performing accurate summaries in the laboratory notebook and keep records using word and excel databases. Incumbent must be able to work independently and with a team of scientists. The position will involve learning and independently performing new techniques at the forefront of cancer therapy and immunobiology.
MINIMUM QUALIFICATIONS
Theoretical background and practical knowledge of molecular biology, immunology and biochemistry and microbiology.
Experience performing molecular and cellular immunology techniques including: DNA isolation, RNA isolation, PCR, RT-PCR, ELISA assays, immunophenotyping, vector purifications, DNA isolation and transfection, PAGE and Western blotting.
Knowledge and experience working with proteins, antibodies and cell culture techniques. Knowledge and experience regarding the use of antibodies in flow cytometry and ELISA.
Experience in the design, construction, production and use of plasmid vectors for recombinant antibody production.
Experience working with small animal and small animal dissection.
Experience in the production, purification and characterization of recombinant antibody molecules.
Experience in the assessment and measurement of Ab binding and affinity by ELISA, flow cytometry and immunoblot.
Experience with assessment of Ab binding affinity by solution phase measurements using the KinExa 3200 instrument.
- < Connections working at University of California San DiegoUC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.