UCSD Layoff from Career Appointment: Apply by 08/23/2022 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 09/01/2022. Eligible Special Selection clients should contact their Disability Counselor for assistance.
UCSD Health Sciences is a $1 billion dollar plus organization encompassing 17 academic departments (15 clinical, 2 basic sciences), 2 preacademic/hospital departments, 2 professional schools (School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences), 2 hospitals, and various other programs and units all dedicated towards fulfilling the Health Sciences missions. The UCSD Department of Cellular and Molecular Medicine (CMM) is one of two basic science units in the School of Medicine where world-class researchers study fundamental cellular processes and pathways using a variety of techniques from classical genetics and fluorescence microscopy to high throughput genomics, systems biology, and crystallography. Our 37 faculty and over 200 postdoctoral scholars, graduate students, and research staff work on the cutting edge of biology, cutting across fields from basic biochemistry and genetics to genomics, systems biology and stem cell biology.
The faculty also play a major role in medical and graduate student training, providing educational and programmatic offerings that span several disciplines and provide diversity to meet the interests of a broad spectrum of students and scholars. The diverse mix of ages, backgrounds, and talents creates a robust work environment with challenging career opportunities and a commitment to continued growth potential. We constantly seek to recruit highly motivated, technologically advanced, and deeply interested individuals who are ready to become a part of our dynamic research and educational environment.
The Institute for Network Medicine [www.inetmed.ucsd.edu] unites several research disciplines to develop disruptive solutions, transform life sciences, and technology and enhance the quality of human life. Founded in Mar of 2018, iNetMed houses three centers, which are collaboratively developing new, human-centered approaches to drug discovery and technological innovation. These positions are geared towards "human-centered drug discovery:
Human-Centered Drug Discovery: The world's drug discovery machinery has a tragic paradox. Academic labs, pharmaceutical companies,6*460 and biotechs have better tools than ever before: supercomputers, genomic sequencers, PCR. Despite these incredible technologies, the drug discovery success rate is lower now than it was in the 1970s. There are two reasons for this: First, the era of 'big data' has not been translated into effective drugs, as was initially expected. Second, current approaches for target discovery rely far too much on inbred animal models (mice, rats, etc.), and drugs that work wonders in these animals. These pre-clinical studies fail far too often, then too late in clinical trials, making the process wasteful and imprecise. To overcome these challenges, iNetMed's two Centers, the Center for Precision Computational System Network (PreCSN) and HUMANOID Center of Research Excellence (CoRE) are working collaboratively to provide an end-to-end new paradigm and platform for drug discovery that begins with target identification (at PreCSN) and ends with target validation in human disease models (at HUMANOID).
The Incumbent will mostly work within the UC San Diego HUMANOID CoRE (humanoid.ucsd.edu), an organoid-based research core that strives to build disease models for testing therapeutics.
Under supervision, research associate will independently perform standard laboratory procedures with adult human stem cells and primary cells, human pluripotent stem cells (hPSCs), including embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), as well as other experimental procedures. Perform a number of standard repetitive laboratory procedures with stem cells, primary cell lines and immortalized cell lines, as needed, with the intent to build disease models that will aid in drug discovery for grand challenges in human diseases that are still without cure.
Use basic molecular biology and microscopy techniques to independently conduct a number of experimental procedures. The research associate will use microscopes, high content imaging, plate-readers, flow cytometers, cell fractionarors, isolators, microfluidic chambers, and available robotics to assay effects of small molecules on stem cells and organoids grown from stem cells will be necessary. The incumbent will perform standard experimental protocols in tissue culture to meet the needs of the research projects, providing ideas and rationale to help improve tests that are unsatisfactory.
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.