The Laboratory for Molecular Medicine (LMM) at Mass General Brigham (MGB) Personalized Medicine is seeking a motivated and experienced individual to work in a cutting-edge environment to serve as a genetic counselor on our team. The LMM is a leading molecular diagnostic laboratory that supports clinicians and researchers across the MGB system, including the flagship institutions of Massachusetts General Hospital and Brigham and Women’s Hospital, and the MGB Biobank. The LMM is also a well-recognized molecular genetics reference laboratory for national and international institutions, and functions as a clinical laboratory and genomic interpretation center for multiple translational research grants. At the LMM, our vision is to lead the implementation of advanced technologies, informatics, and practices into molecular diagnostic testing, focusing on transitioning the emerging aspects of personalized medicine into clinical practice.
The Genetic Counseling Team in collaboration with the Genomic Curation Team is responsible for maintaining excellence and innovation for our clinical testing operations and translational research grants, including panel-based testing, exome sequencing, and genome sequencing. Team members provide thorough review of all data on variants identified during the testing process, using detailed evidenced-based rules for variant classification. The team also performs gene assessment to evaluate the evidence and validity of gene-disease associations. In addition, genetic counselors interpret test results, draft reports and communicate test results to ordering physicians. Genetic counselors assist with content research for new test development, collaborate on projects, generate marketing materials, update documents and text for the website, and also may play a lead role managing LMM components of clinical research projects. For these activities, our genetic counselors interact with geneticists, variant scientists, fellows within the ABMGG and MGP fellowship programs, bioinformaticians, and other laboratory and clinical staff. Opportunities to publish manuscripts with LMM staff and/or external investigators are also available.
PRINCIPAL DUTIES AND RESPONSIBILITIES
Perform variant and gene assessments
Research the significance of variants
Evaluate the evidence for gene-disease associations
Perform literature and data review
Develop a unique knowledge base
Become an expert in variant sciences
Develop an in-depth understanding of the molecular aspects of human diseases
Develop a knowledge of testing technologies used in the laboratory
Provide education and training to lab staff and fellows about variant sciences as needed
Draft test interpretations
Reconcile genetic test results with clinical information and detect any discrepancies between the clinical and molecular findings
Design/maintain reporting templates
Interact with ordering providers in discussing assays and results
Manage clinical research projects
Coordinating LMM activities and managing interactions with external grant team members in conjunction with a laboratory director
Variant assessment and report drafting of variants for both screening and diagnostic purposes
Collaborating with clinicians, specialists, and genetic counselors for delivery of results and referral of patients
Laboratory genetic counseling or variant scientist experience preferred
3+ years of relevant experience preferred
S. from a program accredited by the American Board of Genetic Counseling
Board certified or board eligible by the American Board of Genetic Counseling
Massachusetts State Genetic Counselor Licensure
SKILLS AND ABILITIES REQUIRED
Ability to balance and manage multiple tasks and projects independently; detail-oriented, excellent organizational skills.
Ability to interact effectively with an international network of laboratories and data sources.
Independence, initiative, and problem-solving ability.
Ability work collaboratively as part of team
Knowledge of genetics and genomics
Strong communication skills
Clinical molecular genetic diagnostic laboratory
Currently this position will be remote with the plan of transitioning to an in-office position after the COVID (no earlier than June)
May have supervision of students and interns.
Internal Number: 3140761
About Massachusetts General Hospital
The Laboratory for Molecular Medicine (LMM) is a CLIA-certified molecular diagnostic laboratory, operated by Partners HealthCare Personalized Medicine. The LMM is led by a group of Harvard Medical School-affiliated faculty, geneticists, clinicians, and researchers from Brigham and Women’s Hospital and Massachusetts General Hospital, Partners' founding members. Our mission is to bridge the gap between research and clinical medicine by remaining focused on the following:
Leading the implementation of advanced technologies and practices into molecular diagnostic testing;
Accelerating the adoption of new molecular tests into clinical care;
Incorporating information technology (IT) support into the day-to-day operations of the clinical laboratory; and
Advancing clinical care with our participation in innovative programs, aiming to keep physicians current on and knowledgeable of genetic information relevant to their patients.
Through this work, the LMM is taking the promise of personalized medicine from the lab and into the clinic. Each year, we provide services to more than 4,000 patients and their physicians through over 100 targeted genetic tests, whole gene sequencing, an...d now, whole exome sequencing. From detecting presymptomatic heart conditions such as cardiomyopathy (Pan Cardiomyopathy Panel), to tests for genetic-based hearing loss in children (OtoGenomeTM), and diagnosing lung conditions (PulmoGene Panel), we are working with researchers and physicians to make a difference in the lives of patients.