This position will remain open until a successful candidate has been identified.
Effective 8/24/20, minor revisions have been made to the qualifications that do not change the nature of the position.
UCSD Layoff from Career Appointment: Apply by 08/25/20 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 09/03/20. Eligible Special Selection clients should contact their Disability Counselor for assistance.
The mission of the UCSD Center for Epigenomics is to develop a quantitative and molecular framework to study the function and regulation of the human genome, with the ultimate goal to understand the molecular basis of cancer and other human diseases. Epigenomics is at the forefront of Precision Medicine. The epigenome, a term referring to the state of DNA methylation and the covalent modifications of histone proteins in a cell, plays a central role in regulating the functional output of the genome during development. Changes in the epigenome that result from exposure to stress, pathogenic conditions and during aging can determine the patterns of gene expression and predispose an individual to diseases. Epigenome research promises to significantly improve our understanding of the factors that drive human development and disease. The UCSD Center for Epigenomics will work with researchers on the UCSD campus and beyond to foster the application of epigenomic concepts and technologies to clinical, translational, and basic research.
Under supervision of the Associate Director of Single Cell Genomics, the Single Cell Genomics Research Associate will implement, optimize and perform cutting edge single cell genomic experiments like single cell RNA-seq, single cell ATAC-seq and PAIRED-seq to analyze gene expression and profile the chromatin status in individual cells or nuclei from heterogeneous biological samples including human tissues. The incumbent will participate in experimental design and be responsible for careful record keeping, operating laboratory equipment, troubleshooting, quality control, and periodically summarizing results for supervisors. Additional duties include contributing to laboratory management, organization of laboratory reagents, and maintenance of laboratory equipment.
Theoretical knowledge in molecular biology and biological research or related field as typically attained by a Bachelor's Degree; and/or an equivalent combination of education and experience.
Demonstrated experience with the preparation of next-generation sequencing libraries such as ATAC-seq, ChIP-seq, or RNA-seq.
Demonstrated experience with flow cytometry.
Demonstrated ability to perform molecular biology techniques such as PCR and quantitative PCR.
Hands-on experience with assays such as single cell RNA-seq is a plus, but not required.
Proficient operation of a personal computer and software application, such as MS Word and Excel. Experience in a UNIX command environment is a plus, but not required.
Excellent organizational skills and attention to detail. Proven ability to read, comprehend, and discuss research materials.
Ability to maintain effective working relationships in a diverse laboratory environment. Ability to communicate effectively with clinical staff, research staff, and function as a member of a research team.
Master's degree in molecular biology, genetics, or related field.
Employment is subject to a criminal background check.
Occasional evenings and/or weekends may be required.
Willingness to work with animals, lentivirus, radioactive material, human tissue and standard hazardous laboratory compounds.
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.